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BUTANE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicityyes
Contamination concerns: none
Other HIGH concerns: Multiple, additive exposure sources
Other MODERATE concerns: Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
Other LOW concerns: Data gaps, Occupational hazards

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Synonym(s): N-BUTANE; BUTANE (ACGIH) ; BUTANEN (DUTCH) ; BUTANI (ITALIAN) ; DIETHYL; METHYLETHYLMETHANE; N-BUTANE

Allergies/immunotoxicity

Type of Concern Reference
Human toxicant - strong evidenceCosmetic Ingredient Review Assessments

Multiple, additive exposure sources

Type of Concern Reference
Used in food or as an additive with limited or no toxicity information available FDA Everything Added to Food
Designated as safe for general or specific, limited use in food Cosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

Type of Concern Reference
Classified as a high human health priorityEnvironment Canada Domestic Substance List
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

Type of Concern Reference
Human irritant - strong evidenceCosmetic Ingredient Review Assessments

Data gaps

Type of Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product Cosmetic Ingredient Review Assessments
12,732 studies in PubMed science library may include information on the toxicity of this chemical see search results -> PubMed

Miscellaneous

Type of Concern Reference
Occupational hazards related to handling European Union - Classification & Labelling

Persistence and bioaccumulation

Type of Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Ecotoxicology

Type of Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingBUTANE; [1] ; AND ISOBUTANE [2]F+; R12
Cosmetic Ingredient Review AssessmentsN-BUTANEQQQ01,QQQ11; M-, L, S, IR, GRAS
FDA Everything Added to FoodN-BUTANE• NUL
Environment Canada Domestic Substance ListBUTANEY-Categorization,Y-Human health,High-Health Priority,Y-Persistent,,,,,,
European Union - Banned or Restricted in CosmeticsBUTANEBanned in EU Cosmetics (impurity limit)
National Library of Medicine HazMapN-BUTANESD: No;NT: CNS Solvent Syndrome;TL: 1000 ppm;FL: 4: burns readily;OH: 5048 ppm;OL: 1262 ppm;MA: 1000 ppm;
CIRBUTANEImpurity: butadiene

references
government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
European Union - Banned or Restricted in CosmeticsEC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation."
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Impurities - Open Scientific LiteratureCIR

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