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BENZENE, 1-METHYLETHYL (CUMENE)


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Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Contamination concerns: none
Other HIGH concerns: Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
Other LOW concerns: Ecotoxicology, Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Synonym(s): (1-METHYLETHYL) BENZENE; 2-FENILPROPANO (ITALIAN) ; 2-FENYL-PROPAAN (DUTCH) ; 2-PHENYLPROPANE; BENZENE, (1-METHYLETHYL) - (9CI) ; BENZENE, ISOPROPYL; CUMEEN (DUTCH) ; CUMENE (ACGIH:OSHA) ; CUMOL; ISOPROPILBENZENE (ITALIAN) ; ISOPROPYL BENZENE

Organ system toxicity (non-reproductive)

Type of Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
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Occupational hazards

Type of Concern Reference
Allowed workplace exposures restricted to low dosesEuropean Union - Classification & Labelling

Irritation (skin, eyes, or lungs)

Type of Concern Reference
Classified as irritantEuropean Union - Classification & Labelling

Cancer

Type of Concern Reference
Cancer - not classifiable/not likely to be human carcinogenEPA Integrated Risk Information System (IRIS)

Ecotoxicology

Type of Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling

Data gaps

Type of Concern Reference
Insufficient data to determine safety EPA Integrated Risk Information System (IRIS)
Not assessed for safety in cosmetics by industry panel
100 studies in PubMed science library may include information on the toxicity of this chemical see search results -> PubMed

Miscellaneous

Type of Concern Reference
Occupational hazards related to handling European Union - Classification & Labelling

Neurotoxicity

Type of Concern Reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingCUMENE; [1] ; PROPYLBENZENE [2]R10; Xn; R65; Xi; R37; N; R51-53
Environment Canada Domestic Substance ListBENZENE, (1-METHYLETHYL)-Y-Categorization,Y-Human health,Moderate-Health Priority,,,,,,,
EPA Integrated Risk Information System (IRIS)CUMENED Not classifiable as to human carcinogenicity (1986)
EPA Integrated Risk Information System (IRIS)CUMENECannot Be Determined (1996)
EPA Hazardous Air PollutantsCUMENEHazardous Air Pollutant
National Library of Medicine HazMapCUMENESD: No;HE: Hepatotoxin, Secondary;NT: CNS Solvent Syndrome;PE: 50 ppm (skin);LC: 16000 ppm;TL: 50 ppm;FL: 3: may ignite at ambient temperature;ID: 900 ppm;OH: 0.13 ppm;OL: 0.008 ppm;MA: 50 ppm;
EPA Toxic Release Inventory PBTs(1METHYLETHYL)BENZENEToxic under the EPA's Toxics Release Inventory
US EPA, Air Risk Information Support CenterCUMENESkin or Sense Organ Toxicity Hazards: suspected

references
government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Scorecard.org Toxicity InformationUS EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html

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